A little sneak peek into the “left to right” approach when it comes to the new BoinxTV 2 user interface.
Left-to-right a great, more easily workable, approach - with the possible exception of when using a MacBook where horizontal real estate is at a premium for the main stage. Perhaps you could implement a “layout switch” that users could select.
You will be able to collapse the Layers/sources sidebar and the settings column, just leaving you with your layer stack and your output window.